Top 10 Anime Like The Apothecary Diaries (Kusuriya no Hitorigoto) [2025 List]

Kusuriya no Hitorigoto

Maomao lived a peaceful life with her apothecary father. Until one day, she’s sold as a lowly servant to the emperor’s palace. But she wasn’t meant for a compliant life among royalty. So when imperial heirs fall ill, she decides to step in and find a cure! This catches the eye of Jinshi, a handsome palace official who promotes her. Now, she’s making a name for herself solving medical mysteries!

The Apothecary Diaries has finished airing and it has 24 Episodes. It is also Known as: 薬屋のひとりごと, Drugstore Soliloquy

Genres: Historical , China , Drama , Mystery , Detective , Maid , Seinen , Romance , Slice of Life

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10. Oooku

Oooku

In Edo period Japan (1603 to 1868), a strange new disease called the Redface Pox has begun to prey on the country's men. Within eighty years of the first outbreak, the male population has fallen to a quarter of the total female population. Women have taken on all the roles traditionally granted to men, even that of the Shogun. The men, precious providers of life, are carefully protected and the most beautiful of the men are sent to serve in the Shogun's Inner Chambers.

Ooku: The Inner Chambers has finished airing and it has 10 Episodes. It is also Known as: 大奥, Oooku

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9. Dr. Stone

Dr. Stone

Several thousand years after a mysterious phenomenon that turns all of humanity to stone, the extraordinarily intelligent, science-driven boy, Senku Ishigami, awakens.

Facing a world of stone and the total collapse of civilization, Senku makes up his mind to use science to rebuild the world. Starting with his super strong childhood friend Taiju Oki, who awakened at the same time, they will begin to rebuild civilization from nothing...

Depicting two million years of scientific history from the Stone Age to present day, the unprecedented crafting adventure story is about to begin!

Dr. STONE has finished airing and it has 24 Episodes. It is also Known as: Dr.STONE, Dr. Stone

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8. Ameku Takao no Suiri Karte

Ameku Takao no Suiri Karte

Ten’ikai General Hospital’s Supervisory Department of Diagnostic Pathology handles cases other physicians deem too difficult to treat. It’s also where bizarre mysteries surface, from unexplained illnesses to strange murders even the police can’t solve. At the center of it all is Takao Ameku, a brilliant doctor determined to reveal the shocking truth behind these anomalies.

Ameku M.D.: Doctor Detective has finished airing and it has 12 Episodes. It is also Known as: 天久鷹央の推理カルテ, Ameku Takao's Detective Karte, Ameku Takao no Suiri Karute

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7. Gosick

Gosick

Kazuya Kujou is a foreign student at Saint Marguerite Academy, a luxurious boarding school in the Southern European country of Sauville. Originally from Japan, his jet-black hair and dark brown eyes cause his peers to shun him and give him the nickname "Black Reaper," based on a popular urban legend about the traveler who brings death in the spring.
On a day like any other, Kujou visits the school's extravagant library in search of ghost stories. However, his focus soon changes as he becomes curious about a golden strand of hair on the stairs. The steps lead him to a large garden and a beautiful doll-like girl known as Victorique de Blois, whose complex and imaginative foresight allows her to predict their futures, now intertwined.
With more mysteries quickly developing—including the appearance of a ghost ship and an alchemist with the power of transmutation—Victorique and Kujou, bound by fate and their unique skills, have no choice but to rely on each other.

Gosick has finished airing and it has 24 Episodes. It is also Known as: GOSICK -ゴシック-, Gosick

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6. Saiunkoku Monogatari

Saiunkoku Monogatari

Most people think being born into a noble family means a life of comfort and wealth. That couldn't be further from the truth for Shuurei Kou. Despite the Kou family being an old and important bloodline, they've fallen on hard times. Shuurei's father works as an archivist in the Imperial library, which is a prestigious position, but unfortunately not one that pays much. To put food on the table, Shuurei works odd jobs such as teaching young children or playing live music in a restaurant―and even then, it's barely enough.
Then, one day, a court advisor makes Shuurei an offer. If she becomes the concubine of the new, but lazy, emperor and teaches him how to become a good ruler, then she will receive 500 pieces of gold. Never one to turn down good money, Shuurei accepts the proposition. After all, the new emperor only prefers men so her virtue is safe… or so she thinks.
The more time she spends in the palace, the more her old dream of becoming a court official is reignited. There's only one problem: she's a woman and women do not become government officials. Shuurei may be able to turn the emperor into a good ruler, but will it be at the expense of her own aspirations?

The Story of Saiunkoku has finished airing and it has 39 Episodes. It is also Known as: 彩雲国物語, The Tale of Saiun Country, Story of the Land of Many-Colored Clouds, Kokumono, Saimono, ColourCloud Palace

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5. Honzuki no Gekokujou: Shisho ni Naru Tame ni wa Shudan wo Erandeiraremasen

Honzuki no Gekokujou: Shisho ni Naru Tame ni wa Shudan wo Erandeiraremasen

A certain college girl who's loved books ever since she was a little girl dies in an accident and is reborn in another world she knows nothing about. She is now Myne, the sickly five-year-old daughter of a poor soldier. To make things worse, the world she's been reborn in has a very low literacy rate and books mostly don't exist. She'd have to pay an enormous amounts of money to buy one. Myne resolves herself: If there aren't any books, she'll just have to make them! Her goal is to become a librarian. This story begins with her quest to make books so she can live surrounded by them! Dive into this biblio-fantasy written for book lovers and bookworms!

Ascendance of a Bookworm has finished airing and it has 14 Episodes. It is also Known as: 本好きの下剋上 ~司書になるためには手段を選んでいられません~, Honzuki no Gekokujou: Shisho ni Naru Tame ni wa Shudan wo Erandeiraremasen

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4. Akagami no Shirayuki-hime

Akagami no Shirayuki-hime

Although her name means "snow white," Shirayuki is a cheerful, red-haired girl living in the country of Tanbarun who works diligently as an apothecary at her herbal shop. Her life changes drastically when she is noticed by the silly prince of Tanbarun, Prince Raji, who then tries to force her to become his concubine. Unwilling to give up her freedom, Shirayuki cuts her long red hair and escapes into the forest, where she is rescued from Raji by Zen Wistalia, the second prince of a neighboring country, and his two aides. Hoping to repay her debt to the trio someday, Shirayuki sets her sights on pursuing a career as the court herbalist in Zen's country, Clarines.

Akagami no Shirayuki-hime depicts Shirayuki's journey toward a new life at the royal palace of Clarines, as well as Zen's endeavor to become a prince worthy of his title. As loyal friendships are forged and deadly enemies formed, Shirayuki and Zen slowly learn to support each other as they walk their own paths.

Snow White with the Red Hair has finished airing and it has 12 Episodes. It is also Known as: 赤髪の白雪姫, Akagami no Shirayukihime

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3. Karasu wa Aruji wo Erabanai

Karasu wa Aruji wo Erabanai

In the world of flying crow-humans, trouble is brewing...

YUKIYA is the lackluster second son of a regional boss in the North House territory. His younger brother has overtaken him in academics. He is no good at sword battle, either. Not that this ever bothers him. So it comes as a shock when this boy, who claims to have no ambition whatsoever, is the one chosen to attend the Imperial Prince in Court--. What awaits YUKIYA and his new master is intrigue, murder, a mysterious drug, and invasion from an unexpected enemy. Can they save the world of Yatagarasu (three-legged crows of Japanese myth)?

YATAGARASU: The Raven Does Not Choose Its Master has finished airing and it has 20 Episodes. It is also Known as: 烏は主を選ばない, The Crow Does Not Choose the Lord, Yatagarasu

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2. Akatsuki no Yona

Akatsuki no Yona

Upon her sixteenth birthday, the cheerful Princess Yona intended to tell her doting father of her love for Su-Won, but her life was turned upside down after witnessing him cruelly assassinating her father. Heartbroken by this painful betrayal, Princess Yona fled the palace with her loyal servant Hak. Now, she will go on a quest to gain new allies and protect her beloved people.

Yona of the Dawn has finished airing and it has 24 Episodes. It is also Known as: 暁のヨナ, Yona: The girl standing in the blush of dawn

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1. Koukyuu no Karasu

Koukyuu no Karasu

Deep within the inner palace lives a special consort who does not serve the emperor despite her position as a consort. She is known as the Raven Consort. People who has seen her say she looks like an old women, while others say she looks like a young girl. Stories talk of her use of mysterious arts, and how she can take on any request, be it death curses to finding lost things. Koushun, the current emperor, goes to visit the Raven Consort with that intention. Without knowing that their fated meeting will become a taboo that will overturn history.

Raven in the Inner Palace has finished airing and it has 13 Episodes. It is also Known as: 後宮の烏, Koukyuu no Karasu

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